Chromosome Structure and Analysis

Cell Division: Meiosis and Mitosis

Mitosis vs. Meiosis



in all tissues (somatic cells)

produces diploid somatic cells

1 replication / cell division

short prophase (1 hr)

no pairing of homologs

no recombination

daughter cells are identical

found in primordial germ cells

Only in testes and ovaries

Produces haploids

1 replication / 2 cell divisions

long prophase (50+ yrs)

pairing of homologs in M1

recombination (prophase)

daughter cells different

limited to primary spermatocytes and primary oocytes

Standard Human Karyotype and Cell Cycle

Lymphocyte Cultures (used for chromosome analysis)

Chromosome Structure

Chromosome Banding and FISH