Children as Compromised Hosts
Brief Review of Host Defense Mechanisms
The Newborn Infant
– defect in host defenses due to multiple maturational deficienciesPrimary (Inherited) Immunodeficiency Syndromes
– Most present in infancy and early childhoodSecondary (Acquired) Immunodeficiency Syndromes
Host impairments in the Child with Malignancy
Clinical Examples of Special Susceptibility to Infection in Neonate
How many Infections is Too Many?