Children as Compromised Hosts

Brief Review of Host Defense Mechanisms

The Newborn Infant defect in host defenses due to multiple maturational deficiencies

Primary (Inherited) Immunodeficiency Syndromes Most present in infancy and early childhood

Secondary (Acquired) Immunodeficiency Syndromes

Host impairments in the Child with Malignancy

Clinical Examples of Special Susceptibility to Infection in Neonate

How many Infections is Too Many?