Make your own free website on Tripod.com

Acid-Base Homeostasis: Role of the Respiratory System

Overview of acid-base balance

Chemical control of respiration

Acid-Base Imbalances

Equations and Normal Values

 

Metabolic Acidosis

Metabolic Alkalosis

expected pCO2

1.5 (HCO3-) + 8(2)

0.7 (HCO3-) + 2.0(1.5)

Respiratory Response

pCO2 ß 1.0-1.5 mmHg for every 1 meq/l ß HCO3-

pCO2 Ý 0.6-0.7 mm Hg for every 1 meq/l Ý HCO3-

 

Respiratory Acidosis

Respiratory Alkalosis

acute pH response

pH ß 0.089 for every 10 mmHg Ý pCO2

pH Ý 0.08-0.108 for every 10 mmHg ß pCO2

chronic pH response

pH ß 0.039 for every 10 mmHg Ý pCO2

pH Ý 0.0178 for every 10 mmHg ß pCO2

Buffer Response

HCO3- Ý 1 meq/l for every 10 mmHg Ý in pCO2

HCO3- ß 1.5 meq/l for every 10 mmHg ß in pCO2

Renal Response

HCO3- Ý 2 meq/l for every 10 mmHg Ý in pCO2

HCO3- ß 3.0 meq/l for every 10 mmHg ß in pCO2