Radiation Therapy

 

Diagnosis

Dose

Effect

Metastases

37.5 Gy in 1.5 Gy fractions

26 week survival (vs. 6-12 weeks)

Gliomas

60 Gy

40 week survival (vs. 20 weeks)

Meningiomas

54 Gy in 1.8 Gy fractions

30% recurrence in 4-8 years (vs. 60-75%)

Pituitary

45 Gy in 1.8 Gy fractions

60-90% control, 1/3-//2 hypopituitaristic

AVMs

50Gy

1/3-1/2 respponse

Acoustics

50-54 Gy

50% hearing loss

1-5% CN V, VII loss

 

 

Diagnosis

Dose

 

Pituitary

25 Gy to 50%

optic nerve tolerance- 8-10 Gy, cavernous sinus- 15 Gy

AVM

>15 Gy to 50%

 

Metastases

15-24 Gy to 50%

 

Acoustic

12-13 Gy to 50%

CN VII tolerance 12-13 Gy

Glioma

15-24 Gy to 50%

 

Trigeminal neuralgia

80 Gy to 100%

1 shot

Thalamotomy

120 Gy to 100%

1 shot